Can AMPK mediated suppression of mTORC1 explain the concurrent training effect?
نویسندگان
چکیده
منابع مشابه
Reactive nitrogen species regulate autophagy through ATM-AMPK-TSC2-mediated suppression of mTORC1.
Reactive intermediates such as reactive nitrogen species play essential roles in the cell as signaling molecules but, in excess, constitute a major source of cellular damage. We found that nitrosative stress induced by steady-state nitric oxide (NO) caused rapid activation of an ATM damage-response pathway leading to downstream signaling by this stress kinase to LKB1 and AMPK kinases, and activ...
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ژورنال
عنوان ژورنال: Cellular and Molecular Exercise Physiology
سال: 2013
ISSN: 2049-419X,2049-419X
DOI: 10.7457/cmep.v2i1.e4